5 Simple Statements About LDN-27219 side effects Explained
One particularly attention-grabbing compound is LDN-27219. Even though most tTG inhibitors are intended to bind for the protein crosslinking Lively web site, LDN-27219 as a substitute binds on the nucleotide binding pocket on the enzyme although it's in its shut-state conformation, and stabilizes that conformation to prevent crosslinking activity.7